The foundations of Department “Anatomy, histology and physiology” date back to 1994, when the Faculty of Veterinary medicine was restored within the University of Forestry. Then, under the name “Anatomy, histology and embryology” it was the first department in the Faculty, headed by Professor Georgi Kovachev, Dr.Sc. Then in 1999 the Department was merged with Department of “Pre-clinical Veterinary sciences” (Head Prof. Nikola Sedloev). The newly established department of “Anatomy, histology and embryology” was headed by Prof. Yoncho Kostov, Dr. Sc. Currently, the department provides teaching in the following subjects: “Cytology and histology”, “Embriology”, “Anatomy of domestic animals” (systematic and topographic anatomy), “Animal physiology”. There were separated departments with the same names in the structure of the Faculty of Veterinary medicine of Sofia University “St. Kliment Ohridski” (1923). The same subjects were taught also in the Higher Institute of Veterinary medicine “Prof. Dr. G. Pavlov”, Sofia, until 1974, when the Institute became a faculty within the structure of the Higher Institute of Zootechnics and Veterinary Medicine in Stara Zagora. The subject “Animal ethology” has been taught since 1995. In the new curriculum of the department in 2016, are included and taught two new disciplines – Morphological practice and Clinical anatomy.

The “Animal sciences” department was established in 1995 as a union of basic disciplines necessary for the creation of highly qualified specialists in veterinary medicine. The first head was Prof. Dimitar Stoev Dobrianov, DSc and after that the heads of the Department were Assos. Prof. Malcho Gospodinov Petrov, Prof. Bayko Dimitrov Baykov, Assos. Prof. Iliya Stoyanov Ralchev and prof. Zaprianka Nikolaeva Shindarska. The disciplines studied in the department provide modern knowledges required by each veterinarian in the field of genetics and breeding; biochemistry, general pathology and immunology, technology and hygiene requirements in the manufacture of organic production in livestock breeding; basic animal breeds; pedigree composition; modern feed requirements for domestic animals and the impact of individual feed and supplements on health, reproductive function and animal health and the quality of the animal products obtained. The mandatory subjects taught in the department are thirteen: Professional Ethics; Ecology; Molecular Biology; Nutrition and Agronomy; Genetics and Animal Breeding; Biochemistry; Livestock Breeding; Veterinary Hygiene and Animal Breeding Technology; Immunology; General pathology (Pathophysiology), Public Veterinary Case and Legislation, Forensic Veterinary Medicine. Six optional courses are in the department: History of Veterinary Medicine; Cynology, Working with laboratory animals, welfare and organization of the experiments, Quality and safety of animal feed, Veterinary services of organic livestock breeding, Genetic diagnostic methods in veterinary medicine. The department conducts obligatory students’ summer training on livestock breeding after Third year of education. Scientific research topics in the department are in the field of the assessment of the impact of various factors on the productivity of domestic animals, the management of animal evolution, characteristics of the immune response, analysis and improvement of the legislative base in the field of veterinary medicine and livestock breeding.

In 2021, a joint Department of “Anatomy, Physiology and Animal Sciences” was established on the basis of the Department of “Anatomy, Histology and Physiology “and the Department of “Animal Sciences”.